Myotubularin* family is a group of 16 phosphoinositide-specific phosphatases with specifity towards PtdIns 3P and PtdIns 3,5P2:

     

  1. Myotubularin- MTM (MTM1)

  2. Myotubularin Related Protein1 -MTMR1

  3. Myotubularin Related Protein2 -MTMR2

  4. Myotubularin Related Protein3 -MTMR3

  5. Myotubularin Related Protein4 -MTMR4

  6. Myotubularin Related Protein5 -MTMR5

  7. Myotubularin Related Protein6 -MTMR6

  8. Myotubularin Related Protein7 -MTMR7

  9. Myotubularin Related Protein8 -MTMR8

  10. Myotubularin Related Protein9 -MTMR9

  11. Myotubularin Related Protein10 -MTMR10

  12. Myotubularin Related Protein11 -MTMR11

  13. Myotubularin Related Protein12 -MTMR12

  14. Myotubularin Related Protein13 -MTMR13

  15. Myotubularin Related Protein14 -MTMR14

  16. Myotubularin Related Protein15 -MTMR15

*All sequences except MTMR14 and 15 were found in Laporte's paper

 

PHYLOGENETIC TREE and DOMAIN ORGANIZATION

 

LINKED DISEASES and INTERACTIONS

 

 

OUR DATA , GLYCEROL STOCKS and MAXIPREP STOCKS

 

General subclone strategy used for Directed-Y2H

MTM LITERATURE

updated 15/12/05